NFL odds, lines, picks, spreads, bets, predictions for Week 10, 2023: Model loving Bills, 49ers

Lions, with a 75% success rate, have the highest coverage in the NFL this season.

Week 10 NFL bets could favor the Lions due to their rest advantage over the Chargers, who played on Monday.

Despite the advantages, the Lions are only 2.5-point favorites in Week 10.

Since 2018, the Lions have the best record (11-3) against the spread with a rest advantage.

SportsLine's advanced computer model, with a successful track record, provides advice for Week 10 NFL bets.

The model has earned over $7,000 for $100 players on top-rated NFL picks.

Bills (-7.5) are favored to cover at home against the Broncos, boasting better statistics and an 8-game home winning streak.

49ers (-3) are predicted to cover the spread on the road against the Jaguars after coming off a bye week.

The 49ers, with healthier players, are expected to outperform the Jaguars, who rank 30th in yards allowed.

For confident Week 10 NFL picks, rely on SportsLine's proven computer model for predictions on every game.

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